[Neuroscience] Re: Dendritic spine and Synaptic bouton content

r norman via neur-sci%40net.bio.net (by r_s_norman from _comcast.net)
Wed Feb 21 10:43:28 EST 2007

On 21 Feb 2007 03:22:14 -0800, Cervellone from gmail.com wrote:

>I think i will overuse all your mighty brains for a little while
>longer :-)
>After reviding my opinion on synapses and dendrites as static shells i
>wanted to know whether there are mitochondria in both, synapses and
>Dendrites. In fact they'd better be with all the atp dependent
>processes but how do they get there? It should be difficult to attach
>a Mitochondrion to anterograde transport and squeeze it through the

Presynaptic terminals indeed contain mitochondria.  A paper describing
their significance is  "Synaptic mitochondria are critical for
mobilization of reserve pool vesicles at Drosophila neuromuscular
junctions." by P Verstreken et al. (Neuron. 2005 Aug 4;47(3):365-78)

Google "synaptic mitochondria for more"

As to dendrites, there can be mitochondria there, too.  See "The
importance of dendritic mitochondria in the morphogenesis and
plasticity of spines and synapses" by Z Li et al. (Cell 2004, vol.
119, no6, pp. 873-887)

As to how the mitochondria get where they are supposed to go, look at
"Nerve Cells' Power Plants Caught In A Traffic Jam "

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