Usually intracellular solution has higher osmolarity. If the
osmolarity of your pipette solution is a little bit higher than the
osmolarity of your bath solution, (say 310 versus 300 mOms) cells will
swell slightly and they are easier to path.
Regards!
Jose.
> Thanks for your answer. But I still don't understand the reason for
> using hypoosmol solution. What good do hypoosmol solution?