IUBio Biosequences .. Software .. Molbio soft .. Network News .. FTP

[Neuroscience] Re: SSRIs bind to post-synaptic 5-HT receptors and function as competitive antagonists?

John Hasenkam via neur-sci%40net.bio.net (by johnh from goawayplease.com)
Thu Jan 8 09:44:40 EST 2009


Hey Glen,

Would you mind posting your provisional answer? Depression is a hobby horse 
of mine and given recent controversy over just how SSRIs do what they do I'm 
interested.

Trust the musical marvel is doing well.


John.


> I can now answer my own question, but I'll post the provisional answer for 
> those that might be interested, and I'll provide a reference for those 
> that are interested. Some SSRIs do, indeed, bind at the 5-HT2c receptor, 
> and function as competitive antagonists.



"Glen M. Sizemore" <gmsizemore2 from yahoo.com> wrote in message 
news:4924ad7c$0$28062$ed362ca5 from nr5.newsreader.com...
>
> "r norman" <r_s_norman from _comcast.net> wrote in message 
> news:1f38i4ptqiifib4vmg6d6elrrm30t0t6s0 from 4ax.com...
>> On Wed, 19 Nov 2008 05:26:55 -0500, "Glen M. Sizemore"
>> <gmsizemore2 from yahoo.com> wrote:
>>
>>>
>>>"Glen M. Sizemore" <gmsizemore2 from yahoo.com> wrote in message
>>>news:49234c1f$0$26361$ed362ca5 from nr5.newsreader.com...
>>>> Someone I know claims that SSRIs bind at post-synaptic serotonin
>>>> receptors, and function as competitive antagonists. Anyone know 
>>>> anything
>>>> about this? Thanks ahead of time...
>>>>
>>>> G.
>>>
>>>Correction: SOME SSRIs
>>
>> Could (s)he be thinking of the action of pindolol which is sometimes
>> used in conjunction with SSRIs?
>
> Hi  Dr. Norman,
>
> I can now answer my own question, but I'll post the provisional answer for 
> those that might be interested, and I'll provide a reference for those 
> that are interested. Some SSRIs do, indeed, bind at the 5-HT2c receptor, 
> and function as competitive antagonists.
>
> Cordially,
> Glen 




More information about the Neur-sci mailing list

Send comments to us at biosci-help [At] net.bio.net