"John Hasenkam" <johnh from goawayplease.com> wrote in message
news:-f-dnT--Crq0jPvUnZ2dnUVZ8tPinZ2d from westnet.com.au...
> Hey Glen,
>> Would you mind posting your provisional answer? Depression is a hobby
> horse of mine and given recent controversy over just how SSRIs do what
> they do I'm interested.
>> Trust the musical marvel is doing well.
>>> John.
Hi John,
I am trying to get to the bottom of this alleged binding of some SSRIs to
the 5-HT2c receptor - I may have spoken too soon! I'll get back to you on
this. I am going to have to become educated on this topic since I am going
to be involved in the pre-clinical anti-depressant business. What are you
referring to when you talk about the "recent controversy"?
Yes, Mike is doing well - he's become sort of good on the sax (just a hobby
though). He went to see Perlman the other night - he was supposed to get to
meet him before the performance, but Perlman was not up to meeting people.
Mike spends a lot of time watching Perlman and old tapes of Heifetz - that's
in between times when he is teaching himself to play drums along with an old
Little Feat LP we have.
Hope you are well.
Regards,
Glen
>>>> I can now answer my own question, but I'll post the provisional answer
>> for those that might be interested, and I'll provide a reference for
>> those that are interested. Some SSRIs do, indeed, bind at the 5-HT2c
>> receptor, and function as competitive antagonists.
>>>> "Glen M. Sizemore" <gmsizemore2 from yahoo.com> wrote in message
> news:4924ad7c$0$28062$ed362ca5 from nr5.newsreader.com...>>>> "r norman" <r_s_norman from _comcast.net> wrote in message
>> news:1f38i4ptqiifib4vmg6d6elrrm30t0t6s0 from 4ax.com...>>> On Wed, 19 Nov 2008 05:26:55 -0500, "Glen M. Sizemore"
>>> <gmsizemore2 from yahoo.com> wrote:
>>>>>>>>>>>"Glen M. Sizemore" <gmsizemore2 from yahoo.com> wrote in message
>>>>news:49234c1f$0$26361$ed362ca5 from nr5.newsreader.com...>>>>> Someone I know claims that SSRIs bind at post-synaptic serotonin
>>>>> receptors, and function as competitive antagonists. Anyone know
>>>>> anything
>>>>> about this? Thanks ahead of time...
>>>>>>>>>> G.
>>>>>>>>Correction: SOME SSRIs
>>>>>> Could (s)he be thinking of the action of pindolol which is sometimes
>>> used in conjunction with SSRIs?
>>>> Hi Dr. Norman,
>>>> I can now answer my own question, but I'll post the provisional answer
>> for those that might be interested, and I'll provide a reference for
>> those that are interested. Some SSRIs do, indeed, bind at the 5-HT2c
>> receptor, and function as competitive antagonists.
>>>> Cordially,
>> Glen
>>
