From BIOSCI-REQUEST Fri Jan 9 10:46:59 1998 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12-r-beta/8.6.6) id KAA21111; Fri, 9 Jan 1998 10:46:59 -0800 Received: from snipe.biotech.ufl.org (snipe.biotech.ufl.org [128.227.25.4]) by net.bio.net (8.6.12-r-beta/8.6.6) with ESMTP id KAA21089; Fri, 9 Jan 1998 10:46:57 -0800 Received: from biotech.ufl.org by snipe.biotech.ufl.org (8.7/4.09) id NAA24118; Fri, 9 Jan 1998 13:46:10 -0500 (EST) Message-ID: <34B67012.F1EA962D@biotech.ufl.org> Date: Fri, 09 Jan 1998 13:44:34 -0500 From: Martin Munzer Reply-To: mmunzer@biotech.ufl.org Organization: CyGene, Inc. X-Mailer: Mozilla 4.02 [en]C-DIAL (WinNT; U) MIME-Version: 1.0 To: rust-mil@net.bio.net Subject: New DNA technology Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit New DNA technology The following text is a press release sent out Wednesday through PRNewswire. Contrary to the hype and hysteria over human cloning, these technologies will prove of great benefit to mankind and be available soon. If this does not interest you, please forward it to someone who might be interested. Thanks, Martin Munzer PRESS RELEASE Florida Biotech Companies Fill DNA Technology Gap with New Diagnostic Technologies Alachua, Florida, Jan. 7, /PRNewswire/ -- AGENDA, Inc. and CyGene, Inc., two Florida based biotech companies, have signed a co-licensing agreement to market their next-generation DNA diagnostic technologies. Under the terms of the agreement, AGENDA will market CyGene's patent pending TPA (TM) technology exclusively, and in conjunction with its own RFTA (TM) technology. 1997 was an exceptional year for DNA discoveries. Important genetic sequences, some responsible for diseases such as Alzheimer's, Rheumatoid Arthritis, Cancers, Heart Disease, etc. were recognized. These were added to the huge arsenal of already recognized genetic sequences like HIV, Hepatitis C and numerous contagious or hereditary diseases. One critical tool missing, which would add to the value of these discoveries, is a technology that will quickly, reliably and economically recognize these specific genes when only a few copies are present. AGENDA's RFTA (TM) (patent pending) technology complements TPA (TM) in that both will detect any known genetic sequence while using different methods. These technologies make early reliable diagnosis of HIV, Hepatitis C, cancer, parasitic, viral, bacterial and hereditary diseases a reality. Both processes can be automated, to provide fast and unprecedented first and second opinions regarding the presence or absence of the targeted genes. The ability of these technologies to handle large quantities of DNA or RNA set them apart from other techniques, which are prone to false results. For the first time, very early disease recognition (before the onset of clinical symptoms) is made possible by these next-generation DNA diagnostic technologies. This will open the door to entirely new approaches to disease prevention, management and cure. Early stage diagnosis will make cure scenarios a reality, for many terminal diseases. First generation DNA technology can only reliably detect HIV, 6-7 months post infection. TPA/RFTA (TM) will be able to detect HIV accurately shortly after the time of infection. Similar to computer operating systems, RFTA (TM) and TPA (TM) represent a technology base from which applications can be developed for agricultural, veterinary, health sciences, and human diagnostics. Based on proven molecular biology principles, both technologies can be configured to complete automation and may be performed in tandem using a single sample. AGENDA is actively seeking licensees and companies involved in the design and production of biotech automation equipment. This is the first public announcement of the existence of TPA (TM) and RFTA (TM). Contact: Martin Munzer, Executive VP, 904-418-1616 Email mmunzer@dna-diagnostics.com http://www.dna-diagnostics.com/ and http://www.cygene.com From BIOSCI-REQUEST Sat Jan 10 02:00:09 1998 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12-r-beta/8.6.6) id CAA23895; Sat, 10 Jan 1998 02:00:09 -0800 Received: (from biohelp@localhost) by net.bio.net (8.6.12-r-beta/8.6.6) id CAA23881; Sat, 10 Jan 1998 02:00:05 -0800 Date: Sat, 10 Jan 1998 02:00:05 -0800 From: BIOSCI Administrator Message-Id: <199801101000.CAA23881@net.bio.net> To: rust-mil@net.bio.net Subject: BIOSCI/bionet miniFAQ & Fundraiser (LAST REVISION: 30-JUL-95) This BIOSCI "miniFAQ" is designed to answer the questions that come up the *most frequently*. The main BIOSCI FAQ (Frequently Asked Questions) is accessible on the World Wide Web at URL http://www.bio.net/. If you can not find an answer to your question in this or other documentation, the BIOSCI technical support staff answers e-mail queries sent to biosci-help@net.bio.net We can only answer questions about the use of the newsgroups and mailing lists. We unfortunately do not have the staff to do Internet information searches or answer scientific questions. Please post those to the appropriate BIOSCI/bionet newsgroups. Contents: -------- 0) BIOSCI NEEDS YOUR SUPPORT!! 1) Using the WWW to access the BIOSCI/bionet newsgroups. 2) What to do about "spams," i.e., junk mail, ads, etc. 3) Examples of subscribing and unsubscribing to the mailing lists. 4) The BIOSCI user address and research interest directory. 0) BIOSCI NEEDS YOUR SUPPORT!! ------------------------------ BIOSCI's government funding has been expended, and we are now operating solely from advertising revenue that we have raised from our Web site at http://www.bio.net/. We need just a few minutes of your time to help us serve you. You can do two important things which will take very little time for you individually and will immensely help us continue to help you. First, please use our WWW system at http://www.bio.net/ to access the archives. You can post or reply to messages via your Web browser as described in item #1 below. Your usage helps attract sponsors. If you contact any of our sponsors, please be sure to thank them for supporting BIOSCI. It is critical for them to get this feedback if they are to continue their sponsorship for the long term. Second, if you work for a company or organization that provides products or services of interest to the biology community, please pass this message on to your marketing or marketing communications department or other appropriate group. Please ask them to help support BIOSCI by sponsoring our Web site and explain the uses and benefits of the system to the biology community. If they are interested, they can then contact us for further information at our tech support address, biosci-help@net.bio.net. 1) Using the WWW to access the BIOSCI/bionet newsgroups. -------------------------------------------------------- As of 10 December 1995, all BIOSCI/bionet full newsgroups are accessible through the World Wide Web (WWW) at URL http://www.bio.net. One can read and reply publicly or privately to both recent postings and archived messages through one's Web browser if it is configured properly to send e-mail. Each newsgroup is equipped with its own WAIS index. The main BIOSCI home page also has access to the BIO-JOURNALS Table of Contents database WAIS index and the BIOSCI user address database described in another item further below. 2) What to do about "spams," i.e., junk mail, ads, etc. ------------------------------------------------------- BIOSCI is a set of parallel USENET newsgroups (the "bionet" groups), mailing lists, and a hypermail archive at URL http://www.bio.net/. The same postings are distributed on all media (except for a small number of mailing-list-only groups at net.bio.net). Unfortunately it is becoming a despicable practice on the Internet (by a few people out to make a fast buck) to do automated mass postings to thousands of newsgroups and mailing lists. These attempts to grab free advertising are refered to as "spams" in the usual, somewhat boneheaded, net terminology. USENET is more susceptible to this practice, and many spams originate on the USENET groups and then are passed on to the mailing lists. However, spammers also get lists of mailing addresses and hit these too, so neither medium is immune. What should you do personally if you get junk mail? --------------------------------------------------- Just delete it and move on without reading it further. Filing a protest is becoming increasingly useless because spammers are often disguising the addresses where the messages are sent from. Unless you really understand Internet mail systems, your attempt at protest by sending replies to the message will often end up being sent to the address of an innocent person that the spammer is victimizing. What can BIOSCI/bionet do to protect its newsgroups? ---------------------------------------------------- The only solution currently available is to moderate the newsgroup. If this newsgroup is already moderated, then you are in good shape. Moderation protects the USENET distribution from about 95% of the spams that are being sent to date and protects the mailing lists completely. Moderation means, however, that someone has to take the time to review each message before it goes out. We have set up software here that simply allows the moderator to forward to an address at net.bio.net messages that (s)he wishes to have distributed. This takes no more time than that needed to read the message and pass it on, say about 1 min. per message. Most newsgroups currently have a discussion leader who is responsible for their newsgroup. The discussions leaders and their e-mail addresses are listed in the BIOSCI Information Sheet which is available on the Web at http://www.bio.net/. If a newsgroup is being hit with too many junk postings, please contact the discussion leader for that group and see if there is interest in moderating the group. Please do not assume that by simply posting a complaint to the newsgroup itself, anyone on the BIOSCI staff will act on your complaint. With close to 100 newsgroups to run, the BIOSCI staff has to rely on the discussion leaders of each newsgroup to report problems directly to us at biosci-help@net.bio.net. We will moderate any of our newsgroups if the discussion leader tells us that the readership of the group wishes to do so and if a moderator is willing to do the work. For most BIOSCI/bionet groups, this entails only a few minutes of work each day. Moderating a newsgroup will resolve probably 95% of the junk postings on the USENET distribution. Unfortunately there are easy ways for determined spammers to override the moderation mechanism on USENET, but we can protect our e-mail subscribers from unwanted postings if the newsgroup is moderated. You can also access our newsgroups over the WWW at URL http://www.bio.net. While this Web interface will not stop spammers from trying to post to the groups, this will give you yet another way, besides using USENET news, to keep the junk out of your personal mail files. For those of you with local USENET news systems, the Web interface will also give you faster access to new newsgroups and recent postings. 3) Examples of subscribing and unsubscribing to the mailing lists. ------------------------------------------------------------------ PLEASE NOTE: The BIOSCI management does NOT act on subscription/unsubscription requests that are posted improperly to the newsgroups and mailing lists. People who do this only bother everyone on the lists to no avail. Please be sure to follow the proper procedures below. Gory details are in the BIOSCI Information sheets on the Web at http://www.bio.net. Below we give an example utilizing the METHODS-AND-REAGENTS list at both of our two BIOSCI sites: Users in the Americas and Pacific Rim countries who use the BIOSCI ------------------------------------------------------------------ node at computer net.bio.net: ---------------------------- A) Determine the "listname" which is the <=8 character mail address ^^^^^^^^^^^^^ for the group. These can be found in the BIOSCI Info. Sheet. For the METHODS-AND-REAGENTS group the mailing address is methods@net.bio.net. The listname is the portion of the address to the left of the @ sign, i.e., "methods". The listname is used with the "subscribe" and "unsubscribe" commands illustrated below. B) Mail all commands in the body of a mail message addressed to biosci-server@net.bio.net. Do NOT send commands to the newsgroup posting addresses! Leave the Subject: line blank, any text on it will be ignored. C) In the body of your message put one or more of the following commands with an "end" command on the last line, e.g., subscribe methods unsubscribe methods end Do NOT put your e-mail address or other text on these lines. The server only allows you to cancel your subscription if the address on your mail header matches the address on our mailing list. Please ask for help at biosci-help@net.bio.net if your address has changed, e.g., if you know you are on the list but the server tells you that you are not a member. Users in Europe, Africa, and Central Asia who use the BIOSCI node at -------------------------------------------------------------------- computer daresbury.ac.uk (also known as dl.ac.uk): ------------------------------------------------- To subscribe and unsubscribe to/from the BIOSCI lists, you need to specify the full USENET newsgroup name with "bionet-news." prepended. The USENET newsgroup names are listed in the BIOSCI Information sheet on the Web at http://www.bio.net/. For the METHODS-AND-REAGENTS list the USENET newsgroup name is bionet.molbio.methds-reagnts, thus the appropriate commands are sub bionet-news.bionet.molbio.methds-reagnts unsub bionet-news.bionet.molbio.methds-reagnts These commands are included in a message addressed to mxt@dl.ac.uk, NOT to the newsgroup mailing addresses. As usual, include the text in the body of the message as text on the Subject: line is ignored. To unsubscribe from all the lists at the UK node, use unsub bionet-news Please note that if the address in the list is different than the one in your mail message header, you will not be able to unsubscribe by this method. If you have problems, please mail biosci@daresbury.ac.uk. 4) The BIOSCI user address and research interest directory. ----------------------------------------------------------- Please take this opportunity to add your name, address, and research interest information to the BIOSCI User Address Database if you have not already done so. You can fill out the address form directly through our Web page at URL http://www.bio.net/adrform.html. The address database is reindexed nightly for WWW access (the URL is http://www.bio.net/). If you are not directly on the Internet but can reach it by e-mail, please use our waismail server to access the user directory. waismail use is described above. You can also request a user address form by e-mail from biosci-help@net.bio.net. Please check your database entry from time-to-time to see if your address information is still up-to-date. Because of our limited personnel resources, we ask that you resubmit a *complete* form to revise your entry; we only replace complete entries and do not have resources to edit old forms. From BIOSCI-REQUEST Tue Jan 13 08:36:15 1998 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12-r-beta/8.6.6) id IAA29652; Tue, 13 Jan 1998 08:36:15 -0800 Received: from postoffice.webcow.com (postoffice.webcow.com [206.251.6.250]) by net.bio.net (8.6.12-r-beta/8.6.6) with ESMTP id IAA29649; Tue, 13 Jan 1998 08:36:14 -0800 Received: from cygene-2.biotech.ufl.org ([128.227.25.117]) by postoffice.webcow.com (Post.Office MTA v3.1 release PO203a ID# 0-41990U5000L500S0) with SMTP id AAA10637 for ; Tue, 13 Jan 1998 08:35:23 -0800 Received: by cygene-2.biotech.ufl.org with Microsoft Mail id <01BD2017.14BF9B40@cygene-2.biotech.ufl.org>; Tue, 13 Jan 1998 11:33:34 -0500 Message-ID: <01BD2017.14BF9B40@cygene-2.biotech.ufl.org> From: mmunzer@dna-diagnostics.com (dna-diagnostics.com) To: "'rust-mil@net.bio.net'" Subject: Re: New DNA Technologies Date: Tue, 13 Jan 1998 11:29:55 -0500 MIME-Version: 1.0 Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: quoted-printable Thank you all for your overwhelmingly positive response to our = announcement of new DNA Diagnostic technologies. Due to the volume of = inquiries, we have compiled a series of FAQ's, to respond to the = majority of your questions. We have posted them on our CyGene web site = along with several letters of opinion from professionals who have = reviewed the TPA and RFTA patent documents. RFTA opinion letters will be = posted on our AGENDA site shortly. We will respond to all other inquiries as soon as possible. ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Martin Munzer=20 AGENDA, Inc. http://www.dna-diagnostics.com a.k.a. Advanced Genetic Diagnostic Associates=20 Confirming "Heirlines" Through State of the Art DNA Analysis ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ From BIOSCI-REQUEST Tue Jan 20 04:52:22 1998 Return-Path: BIOSCI-REQUEST Received: (from daemon@localhost) by net.bio.net (8.6.12-r-beta/8.6.6) id EAA04092; Tue, 20 Jan 1998 04:52:22 -0800 Received: from ipw.agrl.ethz.ch (weizen.ethz.ch [129.132.143.254]) by net.bio.net (8.6.12-r-beta/8.6.6) with ESMTP id EAA04083; Tue, 20 Jan 1998 04:52:16 -0800 Received: from peharaj3.plbio.kvl.dk (peharaj3.plbio.kvl.dk [130.225.40.112]) by ipw.agrl.ethz.ch (8.8.5/8.8.5) with SMTP id NAA07971 for ; Tue, 20 Jan 1998 13:51:19 +0100 (MET) Message-ID: <34C4AB77.2D2B@ipw.agrl.ethz.ch> Date: Tue, 20 Jan 1998 14:49:43 +0100 From: "maria.finckh" Reply-To: maria.finckh@ipw.agrl.ethz.ch X-Mailer: Mozilla 3.0 (Win95; I) MIME-Version: 1.0 To: rust-mil@net.bio.net Subject: Invitation to discussion on Future Perspecives on Diversification Strategies Content-Type: text/plain; charset=iso-8859-1 Content-Transfer-Encoding: quoted-printable X-MIME-Autoconverted: from 8bit to quoted-printable by ipw.agrl.ethz.ch id NAA07971 Assoc. Prof. Lisa Munk Dr. Maria Finckh The Royal Veterinary and Agricultural University Department of Plant Biology Thorvaldsenvej 40 DK-1871 Frederiksberg C Tel: (+45) 35 28 33 12/16 Fax: (+45) 35 28 33 10 e-mail: maria.finckh@ipw.agtl.ethz.ch Population Studies of Airborne Pathogens on Cereals as a Means of Improving Strategies for Disease Control. Mixtures Working Group. COST Action 817 Invitation to a discussion on Future Perspectives of Diversification Strategies, 9. Aug. 1998, 8-12am, Edinburgh 19. 1. 1998 Dear Colleague, In 1993, the European Union started funding the COST action 817 on Population Studies of Airborne Pathogens on Cereals as a means of Improving Strategies for Disease Control in which 18 countries and 3 associated institutes are involved. COST actions run usually over five years and are designed to encourage and facilitate Europe-wide co-operation and exchange on topics of general importance. Since the start, five working groups have worked on various topics such as virulence surveys, cultivar and species mixtures, the cereal rust and mildew genome database, partial resistance, epidemiological parameters and fungicide resistances. Scientists from different countries meet once or twice a year to discuss current research and strategies and approaches for joint projects or for workshops. There have also been a number of very fruitful mutual exchanges and trainings between research groups. Within the working group on mixtures we have focused our joint activities mostly on the integration of the research, breeding and extension sector as despite our knowledge on the many possible benefits of mixtures they are not generally used in practice. There are a number of possible reasons for this ranging from practical to legal to psychological that can only be dealt with by involving all concerned groups. Thus, in 1995, we participated at a meeting of the Working Group on Seed Production and Varietal Matters in Germany and in 1996 and 1997, we conducted workshops for breeders and extension agents in Poland and France, respectively. While cultivar and species mixtures are the rule rather than the exception in Poland, they are almost non-existent in France. We have also produced an information brochure for extension agents and growers in Polish, English, French and German. From an informal survey on the use of cultivar and species mixtures in the world and we have obtained some very surprising results (see also: http:/www.uea.ac.uk/nrp/jic/c817home.htm for details). The current COST Action is focusing on airborne pathogens of cereals. However, it has become more and more evident for us in the mixture group that when dealing with diversification strategies, diseases caused by airborne pathogens are only one factor affected by diversification. Many other diseases as well as pests, weeds and even abiotic stresses (such as cold and drought, e.g.) can be reduced by diversification. Therefore, as the COST Action is drawing to its conclusion in 1998, we have decided to expand the discussion to include non-obligate pathogens, species mixtures diversification in time and abiotic stresses into our final meeting for this action. For the next COST application we are also changing our focus to become broader. In view of the 7th International Congress of Plant Pathology in Edinburgh next August 9-16, we have decided to hold part of our next working group meeting in form of a discussion on Future Perspectives of Diversification Strategies right before the congress in order to be able to invite as many interested scientists from around the world to participate and to share their ideas with us. The invited contributions and other presentations should mainly present a platform for discussion, thus we are keeping the presentations short. A preliminary programme of the discussion is attached below. All participants will receive copies of the abstracts of the contributions and detailed notes from the discussion will be made and distributed. The discussion will not be part of the congress itself and will be held at Pollock Halls at Edinburgh University. Thus, we will have to pay for the room and will therefore have to ask you to pay a fee of 20 British Pounds to defray the cost for the facilities and refreshments. We will collect the fee in cash at the discussion and if you have difficulties to pay the fee we can certainly discuss this. For interested participants we will make a group reservation at a restaurant for an informal lunch after the discussion (paid individually). This letter is reaching you either through our address list or the rust-mil network. This means that there are many more colleagues that might be interested in learning about this event and we would greatly appreciate if you made this announcement known to any of your colleagues that might be interested. We will send out a final programme of the discussion, detailed information about the venue and the abstracts in June to all registered participants. Sincerely, Assoc. Prof. Lisa Munk Dr. Maria Finckh Enclosures: =B7 Registration form =B7 Draft for the discussion -------------------------------------------------------------------------= ---------------------------------------- Please register by February 28, 1998, registration by e-mail is much appreciated. Send it to: maria.finckh@ipw.agrl.ethz.ch send registration forms by mail to: Maria Finckh, The Royal Veterinary and Agricultural University, Department of Plant Biology, Thorvaldsenvej 40, DK-1871 Frederiksberg C Registration form for discussion on Future Perspectives of Diversification Strategies 9. Aug. 1998, 8-12am, Edinburgh organised by COST Action 817 Population Studies of Airborne Pathogens on Cereals as a Means of Improving Strategies for Disease Control Mixtures Working Group Name: First Name Address: Phone: Fax: e-mail: I want to participate at the lunch after the discussion (circle one):=20 Yes / No If you would like to contribute to the discussion with a presentation on a specific topic of interest please describe here and we will get into contact with you: -------------------------------------------------------------------------= ----------------------------------------- Preliminary programme for a discussion to be held by the working group on mixtures of COST 817 before the International Congress of Plant Pathology in Edinburgh on Aug. 9 1998 from 8-12am Title: Future perspectives of diversification strategies Introduction: Lisa Munk Non-obligate pathogens above ground Chris Mundt/ Adrian Newton Non-obligate pathogens below ground/ rotations Vivian Vilich=20 Undersowings Wolfe=20 Pasture mixtures nn Polish experience Edward Gacek/ Maria Finckh=20 Abiotic stresses Jill Lenne/ Maria Finckh Relevance of natural ecosystem processes to agriculture nn Presentations will be between 15-30 min to allow the same amount of time for discussion --=20 Dr. Maria Finckh Dept. of Plant Biology KVL Thorvaldsenvej 40 DK 1871 Frederiksberg C Tel: 00 45 35 28 33 12 Fax: 00 45 35 28 33 33 In Switzerland: Institute of Plant Sciences ETH-Z Universitaetsstrasse 2 CH - 8092 Zuerich Tel: 00 41 1 632 38 64/ 48 (secretary) Fax: 00 41 1 632 11 08