Most interesting. Was there any discussion w.r.t. mutation in chromosome
19 in Alzheimers patients DNA and AAV integration.
Thanx
Dan McLeod
LCDC, Canada
Don Haut (c601591 at mizzou1.missouri.edu) writes:
> In article <199509141718.NAA15530 at hobbes.kzoo.edu>, ogston at HOBBES.KZOO.EDU> (Walter Ogston) wrote:
>>> > In article <Pine.A32.3.91.950909123618.24020C-100000 at red.weeg.uiowa.edu>,
>> > volm timothy gerard <tvolm at blue.weeg.uiowa.edu> wrote:
> ...snip!!...
>> How do we explain the difference between a retrovirus and AAV, then?
>> (homework problem).
>> As it turns out, I just came from a meeting where we discussed some of the
> new things that came out of the International Parvovirus Meeting which was
> held last week. AAV integrates into an area of human Chromosome 19; from
> what is know it always integrates somewhere withing about a 1KB area which
> contains two specific sequences, but it does not always integrate at
> exacty the same place within that 1KB area. Also, when we are thinking
> about the above "homework" we should remember, that AAV is not an
> autonomous virus, it requires Adenovirus proteins in order to replicate.
>> Don
>> Don Haut
> Molecular Microbiology and Immunology
> University of Missouri-Columbia
>C601591 at showme.missouri.edu> 314-882-3171
--
Dan McLeod, Ottawa, Ontario, Canada
e-mail dmcleod at hpb.hwc.ca or aq224 at freenet.carleton.ca
