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secondary to tertiary

T. Chyau Liang tliang at utmmg.med.uth.tmc.edu
Wed May 22 03:15:00 EST 1996


In article <4ntc5p$186m at hearst.cac.psu.edu>, userid at psu.edu (First M.
Lastname) wrote:
> We have a protein for which the crystal structure has not been
> determined. Another protein from a family of which our protein is a
> member has had its crystal structure determined.
 
> Does anyone know of a program that I could use to make a prediction of
> the tertiary structure of our protein based on the comparison of the
> secondary structures of the two proteins mentioned above?


Two suggestions:

1. submit your sequence to SWISS-Model

       http://expasy.hcuge.ch/swissmod/SWISS-MODEL.html

P.S.:  If you have not written a letter of support for SWISS-Prot
database, please do so because SWISS-PROT is facing a possible closure. 
See info at: http://expasy.hcuge.ch/sprot/help-sprot.html


2. You can get Modeller from Dr. Andrej Sali

       http://guitar.rockefeller.edu/ftp/pub/modeller/modeller3.README
                                  MODELLER
           PROTEIN MODELLING BY SATISFACTION OF SPATIAL RESTRAINTS

Good luck,

T. Chyau Liang
U. Texas-Houston




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