From sticher from bioc.uzh.ch Mon Apr 6 10:20:59 2009 From: sticher from bioc.uzh.ch (Patrick Sticher) Date: Mon Apr 6 10:21:04 2009 Subject: [Protein-crystallography] 7th International NCCR Symposium on New Trends in Structural Biology Message-ID: <49DA1DDB.5070605@bioc.uzh.ch> Dear colleagues, please be informed that the registration slot for the 7th International NCCR Symposium on New Trends in Structural Biology 7 + 8 September 2009, ETH Z?rich, Lecture Hall HG E7, Z?rich, Switzerland is now open. Online registration is possible directly from the symposium website: www.structuralbiology.uzh.ch/symposium2009 where you will also find further information about this event. Confirmed plenary lecturer to date: Pietro de Camilli, Arthur Horwich, Brian Kobilka, Harry Noller, Anna Marie Pyle, David Wemmer, Masasuke Yoshida Please do not hesitate to contact me anytime if you need further information (sticher@bioc.uzh.ch). With best regards, Patrick Sticher The NCCR Structural Biology is a research initiative of the Swiss Science Foundation. Its research encompasses the fields of recombinant protein technologies, macromolecular structure determination and computational biomolecular sciences with a special focus on membrane proteins and supramolecular assemblies/interactions. 19 research groups from Swiss Universities and Research Institutions participate in this network. www.structuralbiology.uzh.ch/ _________________________________ Dr. Patrick Sticher Moser NCCR Scientific Officer Institute of Biochemistry University of Z?rich Winterthurerstrasse 190 CH - 8057 Z?rich Phone +41 / (0)44 / 635 54 84 Fax +41 / (0)44 / 635 59 08 -- _________________________________ Visit the NCCR on the Internet www.structuralbiology.uzh.ch Dr. Patrick Sticher Moser NCCR Scientific Officer Institute of Biochemistry University of Z?rich Winterthurerstrasse 190 CH - 8057 Z?rich Phone +41 / (0)44 / 635 54 84 Fax +41 / (0)44 / 635 59 08 Mail sticher@bioc.uzh.ch From manolia from stanford.edu Wed Apr 8 23:49:50 2009 From: manolia from stanford.edu (Manolia Margaris) Date: Thu Apr 9 10:24:00 2009 Subject: [Protein-crystallography] ISBMR 9th Course: Biophysics and Structure, Erice-Sicily, 22 Jun-2 Jul '09 Message-ID: We like to bring to your attention the 9th Biophysics and Structure Course of the Int'l School of Biological Magnetic Resonance (ISBMR). We kindly ask you share this information with graduate students, postdoctoral fellows, and other colleagues and interested individuals, particularly in the areas of Structural Biology, NMR, Biophysics, Crystallography, Computational Biology, and Biochemistry. Details follow: COURSE TITLE: ISBMR 9th Course: Biophysics and Structure WHEN: 22 June - 2 July 2009 WHERE: Ettore Majorana Foundation and Centre for Scientific Culture, Erice-Sicily, Italy. URL: http://smrl.stanford.edu/erice2009/ Apply online: http://www.stanford.edu/~manolia/erice2009app.fb * COURSE FORMAT and PURPOSE: The format is an Advanced Study Institute (ASI). This course will provide an overview of physical and structural methods in biology and will present technologies related to pathogen detection and treatment using these methods. Both, basic principles and concrete examples will be presented in a long course format. It is an ideal course for graduate students and postdoctoral fellows. Please note that the structure of the course provides a great opportunity for young scientists to present their work. * TOPICS Include: Principles of NMR spectroscopy; Principles of X-ray diffraction; Single-molecule methods; Cryoelectron Microscopy; Molecular dynamics and other computational approaches; Mass spectrometry; Use of NMR data to calculate protein and nucleic acid structures; New RNA and protein NMR methods; Viral pathogens; Bacterial pathogens; Antivirals; Ribosome structure; Translational mechanism and antibiotics; New technologies to study proteins; Solid state NMR; Peptides as drugs; Membrane proteins as drug targets; Structure-based drug design in biotechnology; NMR and physical studies of pathogenic proteins; Coupling genomics and structural studies. APPLICATION PROCEDURE: Applications are now accepted online: http://www.stanford.edu/~manolia/erice2009app.fb Thank you in advance for your time and consideration. From manolia from stanford.edu Thu Apr 9 01:04:59 2009 From: manolia from stanford.edu (Manolia Margaris) Date: Thu Apr 9 10:24:05 2009 Subject: [Protein-crystallography] ISBMR 9th Course: Biophysics and Structure, Erice-Sicily, 22 Jun-2 Jul '09 Message-ID: <1210ef00-5cee-4e6b-8295-2da1e8d13c97@k38g2000yqh.googlegroups.com> * COURSE FORMAT and PURPOSE: The format is an Advanced Study Institute (ASI). This course will provide an overview of physical and structural methods in biology and will present technologies related to pathogen detection and treatment using these methods. Both, basic principles and concrete examples will be presented in a long course format. It is an ideal course for graduate students and postdoctoral fellows. Please note that the structure of the course provides a great opportunity for young scientists to present their work. * TOPICS Include: Principles of NMR spectroscopy; Principles of X-ray diffraction; Single-molecule methods; Cryoelectron Microscopy; Molecular dynamics and other computational approaches; Mass spectrometry; Use of NMR data to calculate protein and nucleic acid structures; New RNA and protein NMR methods; Viral pathogens; Bacterial pathogens; Antivirals; Ribosome structure; Translational mechanism and antibiotics; New technologies to study proteins; Solid state NMR; Peptides as drugs; Membrane proteins as drug targets; Structure-based drug design in biotechnology; NMR and physical studies of pathogenic proteins; Coupling genomics and structural studies. APPLICATION PROCEDURE: Applications are now accepted online: http://www.stanford.edu/~manolia/erice2009app.fb Thank you in advance for your time and consideration. From sweet from bnl.gov Sat Apr 18 11:50:49 2009 From: sweet from bnl.gov (Robert Sweet) Date: Sat Apr 18 11:53:09 2009 Subject: [Protein-crystallography] A workshop on macromolecular crystallography at the one-micron scale. Message-ID: MX Frontiers at the One Micron Scale July 23 - July 24, 2009 Organized by Dieter Schneider of the Biology Department, and Lonny Berman and Marc Allaire, of the NSLS at Brookhaven National Lab. A web site describing the workshop is here: http://www.nsls.bnl.gov/newsroom/events/workshops/2009/mx/ We invite you to learn from the foremost structural biologists using micro-focused x-ray beams and from the most experienced designers of their beamlines about the unique scientific and experimental capabilities at the one-micron scale. We invite you to take part in discussions of these recent developments. We invite you to weigh in on how they may be translated to the design new crystallographic beamlines at NSLS-II in ways that will optimally serve your needs and fully exploit the uniquely small, stable, and brilliant beams expected to become available here by 2014. This workshop in the 'New Opportunities' series initiated by Qun Shen, the NSLS-II Experimental Facilities Director, will explore structural biology scientific opportunities made possible through the use of micro-beams. It will include studies of difficult-to-crystallize systems and systems for which only small or imperfect crystals could be grown. The impact of using such small beams on mitigating radiation damage of samples will be discussed from first principles to experimental verification. Challenges in producing and using such small beams, and working with very tiny crystals will be explored, including experimental methods that may require development. Speakers -- The following distinguished scientists have agreed to speak and lead discussions: David Eisenberg (University of California at Los Angeles) Gwyndaf Evans (Diamond Light Source, UK) Kenneth Evans-Lutterodt (Brookhaven National Laboratory) Robert Fischetti (Argonne National Laboratory) Elspeth Garman (University of Oxford, UK) Wayne Hendrickson (Columbia University) James Holton (Lawrence Berkeley National Laboartory) Antonio Lanzirotti (Brookhaven National Laboratory) Sean McSweeney (European Synchrotron Radiation Facility, Fr) Colin Nave (Diamond Light Source, UK) Christian Riekel (European Synchrotron Radiation Facility, Fr) Gebhard Schertler (MRC Laboratory for Molecular Biology, UK) Clemens Schulze-Briese (Swiss Light Source) John Spence (Arizona State University) Masaki Yamamoto (RIKEN Harima Institute, SPring-8, Japan) Format and Venue This one-day-and-a-half workshop will be held at Brookhaven National Laboratory. On the evening of July 22, an informal reception at the Brookhaven Center will encourage registration and first contacts. The workshop will convene in earnest on Thursday, July 23, and continue through midday Friday with sessions and several discussions. The Thursday evening dinner will feature an after dinner talk that is part of the workshop program and provide opportunities for more in-depth and personal discussions. The workshop agenda is focused on invited speakers and discussions. However, we welcome relevant poster contributions. Poster boards will be available outside the meeting auditorium during all coffee breaks. We will post abstracts of contributions as well as 8.5 by 11" sized pdf versions of posters on this website. Costs and Registration Please register early using the workshop registration page. The registration fee is a modest $75 and covers breakfast, lunch, and coffee breaks. The cost for dinner on Thursday night - including the after dinner talk - is $50. Sponsors The National Synchrotron Light Source II Project The National Synchrotron Light Source The National Institutes of Health NCRR The National Institutes of Health NIGMS The Department of Energy OBER From cmura from virginia.edu Wed Apr 22 00:32:35 2009 From: cmura from virginia.edu (Cameron Mura) Date: Wed Apr 22 08:18:02 2009 Subject: [Protein-crystallography] Postdoctoral position Message-ID: <0d8b9efa-1f2b-4163-aefc-ab1d9cb01b62@f19g2000yqh.googlegroups.com> A postdoctoral fellow position is available for an individual with a significant amount of training and experience (3+ years) in the methods of structual biology (X-ray crystallography or NMR) and experimental / wet-lab biochemistry, particularly as applied to RNA and protein*RNA complexes. A Ph.D. is not required, but candidates should have a clear record of success (publications), ideally in at least two of the following broad areas: 1) Cloning and protein expression ? purification ? crystallization methodologies, including PCR, site-directed mutagenesis, protein over- expression & purification, protein and RNA crystallization, etc. 2) Biochemical and biophysical methods, such as Western blotting, P32- labelling of oligonucleotides and gel-shift assays, analytical ultracentrifugation, CD spectroscopy, mass spectrometry, light scattering, etc. 3) X-ray Crystallography or NMR, including structure determination and refinement; protein and nucleic acid structure analysis; NMR-based mapping of protein?nucleic acid interactions; expertise in Linux-based operation of software packages commonly used in structural biology (CCP4, CNS, Coot, MODELLER, O, PyMOL, SHELX, etc.). Application materials should be sent via email and should consist of (i) A statement of interest (in cover letter format), specifying interest in either a postdoctoral or longer-term (research staff) position; (ii) A curriculum vitae; and (iii) Three letters of recommendation. Additional information can be found at http://www.virginia.edu/chem/people/faculty/mura .