sequences at telomeres

Michael Lichten lichten%bchem.dnet at DXI.NIH.GOV
Fri Aug 26 10:19:08 EST 1994


Anthony writes:

>Does anyone know if having about 12 bp of spurious DNA (NotI plus half a
>BamHI site) on the TEL end of a linearised YAC arm affects its stability?
> Does the extra sequence mask the telomere, and/or is it chewed back
>until the telomere is exposed?

It is chewed back.





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