Why does FCS induce hyphae in C. albicans

[Douglas Rhoads]

> To:            yeast at net.bio.net
> From:          mdcabl at cc.newcastle.edu.au
> Subject:       Why does FCS induce hyphae in C. albicans
> Date:          6 Jun 95 18:41:02 +1000

> Hi all,
> I have been using fetal calf serum to induce my Candida albicans to become
> hyphal in morphology.  Does anybody know what component it is in the FCS that
> induces the transformation?  Regular Sabouraund both just gives the
> blastoconidia.  I had read where C' can induce this but the FCS has been heat
> inactivated so C' shouldn't be active.  Just curious.
> Thanks,
> Allen Black
> Dept. of Pathology
> Univ. of Newcastle
> mdcabl at cc.newcastle.edu.au
> 
> 
> 

Check out a paper by Barlow, Aldersley and Chattaway in Jr of
General Microbiology 82:261-272.  "Factors present in serum and
seminal plasma which promote germ-tube formation and mycelial
growth of Candida albicans.
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||Doug Rhoads              || Dept. of Biological Sciences||
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