Hi, I'm working with a YAC containing a 180 kb insert, it's derived from pYAC4 and it's maintened in S.cerevisae. I'd like to know if the YACs can recombine with the yeast DNA by the time. Please if someone can help me write to midsilva at usp.br. Thanks. Maria Isabel da Silva Depto.Genetica-FMRP USP-Rib. Preto-SP-Brasil