Re: Evidence for free radical involvement
Another example of some of the pitfalls of the indirect evidence
for free radicals in disease is illustrated by the use of Palosein,
the pharmaceutical formulation of superoxide dismutase in veterinary
medicine.
Veterinarians often use Palosein to treat animals hit by cars.
This does not mean that motor vehicles produce damage by free
radical mechanisms.
Another example: homocysteine, a very potent reducing agent
like most antioxidants, is associated with an increased
incidence of atherosclerosis in humans. This apparently arises
because such agents can reduce oxygen to its radical forms in
autoxidation reactions.
Dr. Dr. Peter Proctor