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Coles and Harris' CoQ10 Study (was Re: A4M Discussion)

Brian Manning Delaney bmdelane at ellis.uchicago.edu
Tue Feb 28 01:02:39 EST 1995

In article <Pine.3.89.9502201701.G10466-0100000 at Gayle-Gaston.tenet.edu>,
Don Ashley <dashley at TENET.EDU> wrote:
>The A4M conference in Vegas produced some stimulating concepts.  It would 
>be beneficial if those topics were discussed and threaded on this 
>newsgroup as well as Longevit newsgp.

I thought this study was quite interesting. CoQ had no effect on max.
life span, but had a fairly significant effect on avg. life span
(experimental animals had about a 20% greater avg. life span).
Autopsies showed that cause of death was essentially the same for both
groups. The effect of CoQ was just to delay the onset of lymphoma. The
amazing thing about this study was the video of the animals at 39
mothns of age: the CoQ animals were _much_ more active, and generally
more "alive" looking. The CoQ animals didn't exhibit hip dysplasia,
but the controls did, etc. The diff. was dramatic. Yet no max. life
span increase.

It makes me wonder how many of the normal changes that occur w/aging
are actually protective. Could it be that all the running around of
the CoQ animals somehow accelerated aging, compared w/the controls?
There are many other possible explanations, of course.

(Still, the blind attempt by some people to get all hormone levels
back to "youthful" levels might be unwise.)

Brian M. Delaney <b-delaney at uchicago.edu> [DO NOT cc: articles to me.]
<bmdelane at midway.uchicago.edu> [Wrists: "Leave unambiguous typos."]
Note: All statements in this article are in jest; they are not
statements of fact. * "Mein Genie ist in meinen Nuestern." -Nietzsche.

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